Gestational diabetes mellitus: taking it to heart

Prim Care Diabetes. 2011 Jul;5(2):81-8. doi: 10.1016/j.pcd.2010.10.002. Epub 2010 Nov 23.

Abstract

Globally, cardiovascular disease (CVD) accounts for 1/3 of all deaths to women. While much research identifies the increased risk in CVD associated with pre-diabetes measurements, there is growing interest in the role of gestational diabetes mellitus (GDM)-a condition of glucose intolerance diagnosed during pregnancy-as a potential CVD risk factor. This article reviews existing evidence supporting this association, particularly regarding GDM and type 2 diabetes, hypertension, atherogenic dyslipedmia, and CVD events. Finally, it discusses the research and clinical ramifications of identifying GDM as a CVD risk factor, highlighting the need for more rigorous research on this topic.

Publication types

  • Review

MeSH terms

  • Biomarkers / blood
  • Cardiovascular Diseases / blood
  • Cardiovascular Diseases / epidemiology
  • Cardiovascular Diseases / etiology*
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / epidemiology
  • Diabetes Mellitus, Type 2 / etiology*
  • Diabetes, Gestational* / blood
  • Diabetes, Gestational* / epidemiology
  • Evidence-Based Medicine
  • Female
  • Humans
  • Pregnancy
  • Prognosis
  • Risk Assessment
  • Risk Factors
  • Time Factors

Substances

  • Biomarkers