The role of inflamed adipose tissue in the insulin resistance

Cell Biochem Funct. 2010 Dec 2;28(8):623-31. doi: 10.1002/cbf.1706.

Abstract

In this article, we discuss inflammation associated with adipose tissue dysfunction as a potential link with obesity-related insulin resistance, and how obesity-related inflammatory components, such as immune cells, cytokines/chemokines and adipocytokines, induce obesity-related pathologies.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adipokines / metabolism
  • Adipose Tissue, White / immunology
  • Adipose Tissue, White / physiopathology*
  • Animals
  • Cytokines / metabolism
  • Humans
  • Inflammation / immunology
  • Inflammation / physiopathology*
  • Insulin Resistance*
  • Lipodystrophy / pathology
  • Lipodystrophy / physiopathology
  • Obesity / physiopathology

Substances

  • Adipokines
  • Cytokines