Gene regulation: global transcription rates scale with size

Huzefa Dungrawala; Arkadi Manukyan; Brandt L Schneider

doi:10.1016/j.cub.2010.09.064

Gene regulation: global transcription rates scale with size

Curr Biol. 2010 Nov 23;20(22):R979-81. doi: 10.1016/j.cub.2010.09.064.

Authors

Huzefa Dungrawala¹, Arkadi Manukyan, Brandt L Schneider

Affiliation

¹ Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.

PMID: 21093791
DOI: 10.1016/j.cub.2010.09.064

Abstract

Is bigger better? Scientists have long puzzled over the potential relationship between cell size and the rate of mRNA production. A recent report builds a strong case that global transcription rates scale with size.

Publication types

Comment

MeSH terms

Cell Size
DNA, Fungal / metabolism
Gene Expression Regulation, Fungal / physiology*
Oligonucleotide Array Sequence Analysis
RNA, Messenger / metabolism
Schizosaccharomyces / cytology
Schizosaccharomyces / genetics*
Schizosaccharomyces pombe Proteins / genetics*
Schizosaccharomyces pombe Proteins / metabolism
Transcription, Genetic*

Substances

DNA, Fungal
RNA, Messenger
Schizosaccharomyces pombe Proteins