Synthesis of poly(amino)ester dendrimers via active cyanomethyl ester intermediates

J Org Chem. 2010 Dec 17;75(24):8685-8. doi: 10.1021/jo101739x. Epub 2010 Nov 17.

Abstract

A novel strategy for the synthesis of poly(amino)ester dendrimers was developed on the basis of active cyanomethyl ester intermediates and an iteration of four consecutive steps of deprotection, activation, transesterification, and scavenging.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Dendrimers / chemical synthesis*
  • Dendrimers / chemistry
  • Esterification
  • Esters
  • Molecular Structure
  • Nitriles / chemistry*
  • Polyamines / chemical synthesis*
  • Polyamines / chemistry

Substances

  • Dendrimers
  • Esters
  • Nitriles
  • Polyamines