Nanotechnologies are an important set of new technologies no longer at a very early stage in their development. The financial support for R&D in this domain is greater than a few Giga Euros/year for innovation and considerably lower (less than 1-2%) for risk management. At the factory level, As Low As Reasonably Achievable (ALARA) methods have to be used in order to protect workers against possible exposure. New "short-term" toxicological studies show that nano-particles are seldom exempt of effects in humans... Thus, for the general population, more and more anxious about the future, nanotechnologies are the object of numerous debates. Ultimately, the population is asking governmental bodies to take the required preventive measures. Social pressure is now initiated by the public towards innovative industries, which have to prove, before the marketing stage, the absence of any risk for the users and demonstrate a safety driven governance.