Surfactant-Modified MFI-Zeolite Nanosheets (SMZN) were used for the first time as anion-exchangers, in the case of nitrate ion removal. The SMZN material is characterized by high anionic exchange capacity and removal efficiency compared to classical SMZ prepared from clinoptilolite. The SMZN material is easily regenerated and could be probably employed to remove other anionic pollutants.