Three fatal cases of pandemic 2009 influenza A virus infection in Shenzhen are associated with cytokine storm

Xiao-Wen Cheng; Juan Lu; Chun-Li Wu; Li-Na Yi; Xu Xie; Xiang-Dong Shi; Shi-Song Fang; Hong Zan; Hsiang-Fu Kung; Ming-Liang He

doi:10.1016/j.resp.2010.11.004

Three fatal cases of pandemic 2009 influenza A virus infection in Shenzhen are associated with cytokine storm

Respir Physiol Neurobiol. 2011 Jan 31;175(1):185-7. doi: 10.1016/j.resp.2010.11.004. Epub 2010 Nov 11.

Authors

Xiao-Wen Cheng¹, Juan Lu, Chun-Li Wu, Li-Na Yi, Xu Xie, Xiang-Dong Shi, Shi-Song Fang, Hong Zan, Hsiang-Fu Kung, Ming-Liang He

Affiliation

¹ The Shenzhen Center for Disease Control and Prevention, Shenzhen, China.

PMID: 21075220
DOI: 10.1016/j.resp.2010.11.004

Abstract

China had taken strict measures for pandemic 2009 H1N1 infection with enhanced surveillance and hospital isolation since April 2009. In Shenzhen, over 1200 confirmed cases of H1N1 infection were identified. Three young patients died of severe pneumonia. Among them, two boys developed neurological complications. Cytokine storm seemed an important cause.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Child
China / epidemiology
Cytokines / blood*
Fatal Outcome
Female
Humans
Influenza A Virus, H1N1 Subtype / pathogenicity*
Influenza, Human* / blood
Influenza, Human* / epidemiology
Influenza, Human* / physiopathology
Male
Pandemics*
Young Adult

Substances

Cytokines