Left ventricular torsion by two-dimensional speckle tracking echocardiography in patient with a-type amyloid heart disease

Abstract

Amyloidosis is a clinical disorder caused by extracellular and or intracellular deposition of insoluble abnormal amyloid fibrils that alter the normal function of tissues. Amyloid A amyloidosis is the most common form of systemic amyloidosis worldwide The heart may be affected in systemic AL amyloidosis, but also more rarely in A amyloidosis. In this report, we presented a patient with A-type amyloid heart disease who had dynamic left ventricular outflow tract obstruction mimicking hypertrophic obstructive cardiomyopathy. We also investigated left ventricular torsion, untwisting rate and left ventricular longitudinal global strain by two-dimensional speckle tracking echocardiography.