Researchers are testing different treatments to induce modifications in both chemical composition and topography of implant surface, with the aim to ameliorate bone-to-implant contacts and hence improve osseointegration processes and biomechanical properties in the short and long-term. Aim of the present research was the evaluation of MG63 osteoblast-like cells behaviour on polymeric coatings, electrosynthesized on titanium substrates, differently modified in order to improve implant performances both in terms of osseointegration and infection prevention. Cell viability data and scanning electron microscopy morphological observations were consistent with a good compatibility of modified electrosynthesized coatings and suggest the use of this procedure to produce new bioactive titanium coatings for implant surgery.