[A protein interaction network and cell signaling pathways activated by muramyl peptides]

E A Meshcheriakova; T M Andronova; V T Ivanov

doi:10.1134/s1068162010050018

[A protein interaction network and cell signaling pathways activated by muramyl peptides]

Bioorg Khim. 2010 Sep-Oct;36(5):581-95. doi: 10.1134/s1068162010050018.

[Article in Russian]

Authors

E A Meshcheriakova, T M Andronova, V T Ivanov

PMID: 21063445
DOI: 10.1134/s1068162010050018

Abstract

Review is devoted to studying the interaction muramyl peptides with protein components of immune system cells. Systems analysis of published results may be useful to select not only the strategy to further explore the function of this class of glycopeptides, but their use in clinical practice.

Publication types

English Abstract
Review

MeSH terms

Acetylmuramyl-Alanyl-Isoglutamine / pharmacology*
Adaptive Immunity / drug effects
Adaptive Immunity / immunology
Adjuvants, Immunologic / pharmacology*
Animals
Cell Line
Humans
Immunity, Innate / drug effects
Immunity, Innate / immunology
Intracellular Signaling Peptides and Proteins / metabolism*
Mitogen-Activated Protein Kinases / metabolism
NF-kappa B / metabolism
Nod2 Signaling Adaptor Protein / metabolism
Protein Interaction Mapping
Signal Transduction / drug effects*
Signal Transduction / immunology
Toll-Like Receptors / metabolism

Substances

Adjuvants, Immunologic
Intracellular Signaling Peptides and Proteins
NF-kappa B
Nod2 Signaling Adaptor Protein
Toll-Like Receptors
Acetylmuramyl-Alanyl-Isoglutamine
Mitogen-Activated Protein Kinases