Proteomics and systems biology to tackle biological complexity: Yeast as a case study

Lilia Alberghina; Claudia Cirulli

doi:10.1002/pmic.201000114

Proteomics and systems biology to tackle biological complexity: Yeast as a case study

Proteomics. 2010 Dec;10(24):4337-41. doi: 10.1002/pmic.201000114.

Authors

Lilia Alberghina¹, Claudia Cirulli

Affiliation

¹ Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, Italy. lilia.alberghina@unimib.it

PMID: 21061424
DOI: 10.1002/pmic.201000114

Abstract

In this note we discuss how, by using budding yeast as model organism (as has been done in the past for biochemical, genetics and genomic studies), the integration of "omics" sciences and more specifically of proteomics with systems biology offers a very profitable approach to elucidating regulatory circuits of complex biological functions.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cell Cycle
Proteome / metabolism*
Proteomics
Saccharomyces cerevisiae / cytology
Saccharomyces cerevisiae / metabolism
Saccharomyces cerevisiae / physiology*
Saccharomyces cerevisiae Proteins / metabolism*
Systems Biology

Substances

Proteome
Saccharomyces cerevisiae Proteins