Lymphoepithelioma-like carcinoma of the urinary bladder

J Korean Med Sci. 2010 Nov;25(11):1672-5. doi: 10.3346/jkms.2010.25.11.1672. Epub 2010 Oct 26.

Abstract

A 78-yr-old woman presented with gross hematuria for 2 weeks. On cystoscopy, a frond-like mass was observed at the bladder trigone. Transurethral resection of bladder tumor was performed for the mass. Histopathological findings showed that 90% of lesions were lymphoepithelioma-like carcinoma (LELCA) and a few lesions were non-invasive transitional cell carcinoma. On microscopy, syncytial growth pattern and indistinct cytoplasmic borders were observed with the severe infiltration of lymphoid cells. The case was followed-up for 8 months without recurrence. This is the first report of a LELCA case in Korea.

Keywords: Lymphoepithelioma; Lymphoepithelioma-like carcinoma; Urinary Bladder.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antigens, CD20 / metabolism
  • B-Lymphocytes / immunology
  • B-Lymphocytes / metabolism
  • CD3 Complex / metabolism
  • Carcinoma / diagnosis*
  • Carcinoma / pathology
  • Carcinoma / surgery
  • Female
  • Hematuria / etiology
  • Humans
  • Keratin-20 / metabolism
  • Keratin-7 / metabolism
  • T-Lymphocytes / immunology
  • T-Lymphocytes / metabolism
  • Tomography, X-Ray Computed
  • Urinary Bladder Neoplasms / diagnosis*
  • Urinary Bladder Neoplasms / pathology
  • Urinary Bladder Neoplasms / surgery

Substances

  • Antigens, CD20
  • CD3 Complex
  • Keratin-20
  • Keratin-7