Obstructive sleep apnea syndrome (OSAS) is a complex disease, which frequently links and interacts with other conditions, such as cardiovascular disease, cerebrovascular disease, chronic obstructive pulmonary disease, erectile dysfunction. OSAS has a significant response on daily activities, including an increased risk for acute cardiovascular events, metabolic and respiratory events and a higher rate of road accidents. In this article, we intend to present some data about the impact of continuous positive pressure therapy (CPAP) on quality of life of patients with OSAS and it's systemic comorbidities, while trying to draw a warning as to the importance of early initiation of CPAP treatment, which, despite the increased cost, remains the gold standard in treating patients with OSAS.