Deferiprone reduces hemosiderin deposits in the brain of a patient with superficial siderosis

M Levy; R H Llinas

doi:10.3174/ajnr.A2331

Deferiprone reduces hemosiderin deposits in the brain of a patient with superficial siderosis

AJNR Am J Neuroradiol. 2011 Jan;32(1):E1-2. doi: 10.3174/ajnr.A2331. Epub 2010 Nov 4.

Authors

M Levy¹, R H Llinas

Affiliation

¹ Department of Neurology, Johns Hopkins University, Baltimore, Maryland, USA. mlevy@jhmi.edu

Abstract

A man with superficial siderosis showed improvement in symptoms and reduction in hemosiderin by MR imaging following treatment with deferiprone, a lipid-soluble iron chelator.

Publication types

Case Reports

MeSH terms

Aged
Brain / drug effects
Brain / metabolism
Deferiprone
Hemosiderin / metabolism*
Humans
Iron Chelating Agents / therapeutic use
Magnetic Resonance Imaging / methods
Magnetic Resonance Spectroscopy / methods
Male
Pyridones / therapeutic use*
Siderosis / drug therapy*
Siderosis / metabolism*
Tissue Distribution
Treatment Outcome

Substances

Iron Chelating Agents
Pyridones
Deferiprone
Hemosiderin