Comparison of corneal thickness and haze in DSAEK and penetrating keratoplasty

Cornea. 2011 Mar;30(3):287-90. doi: 10.1097/ICO.0b013e3181eeafd6.

Abstract

Purpose: To compare corneal thickness and haze in Descemet stripping automated endothelial keratoplasty (DSAEK) and penetrating keratoplasty (PK).

Methods: This study included 30 consecutive patients undergoing DSAEK (18 patients) and PK (12 patients). Central corneal thickness and corneal haze were analyzed longitudinally by Pentacam (Oculus, Wetzlar, Germany) at 2 weeks, 1 month, and 3 months after grafting.

Results: The mean age of patients in the DSAEK group was 71.42 ± 9.91 years (range, 55-85 years) and in the PK group was 60.58 ± 16.58 years (range, 31-81 years). Two weeks, 1 month, and 3 months after surgery, the cornea was significantly thicker in the DSAEK group compared with the PK group (P < 0.01). Two weeks, 1 month, and 3 months after the operation, the cornea had significantly more haze in the DSAEK group compared with the PK group (P < 0.05). Haze in the DSAEK group was mainly observed in the subepithelial stroma.

Conclusions: DSAEK grafts were significantly thicker with increased haze for up to 3 months after surgery. Scheimpflug system is available for quantifying not only corneal thickness but also corneal haze after various keratoplasty procedures.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Body Weights and Measures
  • Cornea / pathology*
  • Corneal Diseases / surgery
  • Corneal Opacity / diagnosis*
  • Corneal Opacity / etiology
  • Descemet Stripping Endothelial Keratoplasty*
  • Female
  • Humans
  • Keratoplasty, Penetrating*
  • Male
  • Middle Aged
  • Photography
  • Postoperative Complications*
  • Refraction, Ocular / physiology
  • Visual Acuity / physiology