Cell microcarriers and microcapsules of stimuli-responsive polymers

J Control Release. 2011 Feb 10;149(3):209-24. doi: 10.1016/j.jconrel.2010.09.023. Epub 2010 Oct 28.

Abstract

Cell microcarriers and microcapsules have presented a wide range of potential applications. This article overviews their role in biotechnology with focus on the progress accomplished using stimuli-responsive polymers. Key properties of cell microcarriers and microcapsules are identified, followed by a description of the chemistry and gel formation mechanism of some of the stimuli-responsive polymers used to design them. Production methods are introduced and characterization techniques for evaluating such microsystems are equally presented.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Biocompatible Materials / chemistry
  • Biocompatible Materials / metabolism
  • Biocompatible Materials / pharmacokinetics
  • Capsules / chemistry*
  • Capsules / metabolism
  • Capsules / pharmacokinetics
  • Drug Carriers / chemistry*
  • Drug Carriers / metabolism
  • Drug Carriers / pharmacokinetics
  • Drug Compounding / methods*
  • Humans
  • Polymers / chemistry*
  • Polymers / metabolism
  • Polymers / pharmacokinetics

Substances

  • Biocompatible Materials
  • Capsules
  • Drug Carriers
  • Polymers