Genome sequence conservation of Hendra virus isolates during spillover to horses, Australia

Glenn A Marsh; Shawn Todd; Adam Foord; Eric Hansson; Kelly Davies; Lynda Wright; Chris Morrissy; Kim Halpin; Deborah Middleton; Hume E Field; Peter Daniels; Lin-Fa Wang

doi:10.3201/eid1611.100501

Genome sequence conservation of Hendra virus isolates during spillover to horses, Australia

Emerg Infect Dis. 2010 Nov;16(11):1767-9. doi: 10.3201/eid1611.100501.

Authors

Glenn A Marsh¹, Shawn Todd, Adam Foord, Eric Hansson, Kelly Davies, Lynda Wright, Chris Morrissy, Kim Halpin, Deborah Middleton, Hume E Field, Peter Daniels, Lin-Fa Wang

Affiliation

¹ Australian Animal Health Laboratory, Geelong, Victoria, Australia. glenn.marsh@csiro.au

Abstract

Bat-to-horse transmission of Hendra virus has occurred at least 14 times. Although clinical signs in horses have differed, genome sequencing has demonstrated little variation among the isolates. Our sequencing of 5 isolates from recent Hendra virus outbreaks in horses found no correlation between sequences and time or geographic location of outbreaks.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Australia / epidemiology
Chiroptera*
Disease Outbreaks / veterinary
Genome, Viral*
Hendra Virus / genetics*
Henipavirus Infections / epidemiology
Henipavirus Infections / veterinary*
Henipavirus Infections / virology
Horse Diseases / epidemiology
Horse Diseases / virology*
Horses
Phylogeny