Pharmacologic treatment for low back pain: one component of pain care

Phys Med Rehabil Clin N Am. 2010 Nov;21(4):793-800. doi: 10.1016/j.pmr.2010.06.013.

Abstract

Analgesic medications are commonly used for low back pain (LBP). Evidence on the efficacy of pharmacologic therapy for LBP comes from clinical trials that have many limitations, including short-term studies and selective trial populations. Evidence currently supports the use of short-term pharmacologic treatment for LBP. However, the safety and efficacy of long-term pharmacologic therapy for LBP is uncertain and therefore best used with caution, monitoring, and as one component of a comprehensive paincare approach emphasizing rehabilitation.

Publication types

  • Review

MeSH terms

  • Acetaminophen / therapeutic use
  • Amines / therapeutic use
  • Analgesics, Non-Narcotic / therapeutic use
  • Analgesics, Opioid
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Anticonvulsants / therapeutic use
  • Antidepressive Agents, Tricyclic / therapeutic use
  • Cyclohexanecarboxylic Acids / therapeutic use
  • Gabapentin
  • Humans
  • Low Back Pain / drug therapy*
  • Neuromuscular Agents / therapeutic use
  • gamma-Aminobutyric Acid / therapeutic use

Substances

  • Amines
  • Analgesics, Non-Narcotic
  • Analgesics, Opioid
  • Anti-Inflammatory Agents, Non-Steroidal
  • Anticonvulsants
  • Antidepressive Agents, Tricyclic
  • Cyclohexanecarboxylic Acids
  • Neuromuscular Agents
  • Acetaminophen
  • gamma-Aminobutyric Acid
  • Gabapentin