Abstract
Total synthesis of Phytophthora mating hormone α1 (1) has been demonstrated. The required stereochemistries (methyl) are achieved by applying CuI-(S)-Tol-BINAP-catalyzed conjugate addition of Grignard reagents to α,β-unsaturated esters.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Catalysis
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Diterpenes / chemical synthesis*
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Diterpenes / chemistry
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Hormones / chemical synthesis*
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Hormones / chemistry
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Molecular Structure
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Phytophthora / chemistry*
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Stereoisomerism
Substances
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Diterpenes
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Hormones
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mating hormone alpha1, Phytophthora