Abstract
DOR, a nuclear receptor co-activator conserved from flies to humans, provides a molecular connection between ecdysone and insulin signaling, two important pathways controlling developmental timing and growth, respectively.
Copyright © 2010 Elsevier Ltd. All rights reserved.
MeSH terms
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Animals
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DNA-Binding Proteins / metabolism*
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DNA-Binding Proteins / physiology
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Drosophila Proteins / metabolism*
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Drosophila Proteins / physiology
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Drosophila melanogaster / growth & development*
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Ecdysone / metabolism*
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Homeostasis / physiology*
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Insulin / metabolism*
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Models, Biological
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Receptors, Steroid / metabolism
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Signal Transduction / physiology*
Substances
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DNA-Binding Proteins
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DOR protein, Drosophila
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Drosophila Proteins
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Insulin
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Receptors, Steroid
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ecdysone receptor
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Ecdysone