[Remifentanil is useful for cardiovascular stability during cesarean delivery in a parturient with Marfan's syndrome]

Masui. 2010 Oct;59(10):1305-7.
[Article in Japanese]

Abstract

A 25-year-old parturient with Marfan's syndrome was scheduled for cesarean delivery. She suffered with severe scoliosis and asymptomatic aortic root dilatation. To establish a cardiovascular stability and prevent aortic dissection perioperatively, we selected the use of remifentanil, an ultra-short acting opioid analgesic with general anesthesia. General anesthesia was induced with remifentanil (0.2 microg x kg(-1) x min(-1)), propofol (100 mg), and vecuronium bromide (10 mg). Anesthesia was maintained with 100% O2, sevoflurane (1-1.5%), and remifentanil (0.2-0.25 microg x kg(-1) x min(-1)). She remained hemodynamically stable during surgery. A lively infant was delivered and Apgar scores were 8 and 9 at 1 and 5 min, respectively. Their post-delivery courses were uneventful. Remifentanil was useful for anesthetic management in a pregnant patient with Marfan's syndrome undergoing cesarean delivery, although attention to infant's respiratory condition should be paid because remifentanil can cross the placenta.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Analgesics, Opioid / pharmacology*
  • Anesthesia, General / methods*
  • Anesthesia, Obstetrical / methods*
  • Cesarean Section*
  • Female
  • Hemodynamics / drug effects
  • Humans
  • Marfan Syndrome / complications*
  • Piperidines / pharmacology*
  • Pregnancy
  • Remifentanil

Substances

  • Analgesics, Opioid
  • Piperidines
  • Remifentanil