Access to β,γ-diamino acids. Application to the synthesis of 3-deoxyaminostatine

Org Biomol Chem. 2011 Jan 21;9(2):394-9. doi: 10.1039/c0ob00370k. Epub 2010 Oct 19.

Abstract

The synthesis of orthogonally protected diastereo- and enantiopure β,γ-diamino acids starting from natural α-amino acids is described, as well as its application to the synthesis of fully protected 3-deoxyaminostatine.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acids, Diamino / chemical synthesis
  • Amino Acids, Diamino / chemistry*
  • Models, Molecular
  • Molecular Structure
  • Pyrrolidines / chemical synthesis

Substances

  • 3-deoxyaminostatine
  • Amino Acids, Diamino
  • Pyrrolidines
  • pyrrolidine