Targeted modulation of the neuroinflammatory response after spinal cord injury: the ongoing quest for the "holy grail"

Am J Pathol. 2010 Dec;177(6):2685-7. doi: 10.2353/ajpath.2010.100408. Epub 2010 Oct 15.

Abstract

This Commentary discusses the role of inflammation after spinal cord injury.

Publication types

  • Comment

MeSH terms

  • Animals
  • Complement Factor B / antagonists & inhibitors
  • Complement Factor B / genetics
  • Complement Factor B / immunology
  • Complement Pathway, Alternative / immunology
  • Complement Pathway, Alternative / physiology
  • Humans
  • Immunotherapy / methods
  • Immunotherapy / trends
  • Mice
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Models, Biological
  • Molecular Targeted Therapy / methods
  • Molecular Targeted Therapy / trends*
  • Myelitis / etiology
  • Myelitis / immunology*
  • Myelitis / pathology
  • Myelitis / therapy*
  • Spinal Cord Injuries / complications
  • Spinal Cord Injuries / immunology*
  • Spinal Cord Injuries / therapy*

Substances

  • Complement Factor B