Fabrication and characterization of a radiation sensor based on bacteriorhodopsin

Biosens Bioelectron. 2011 Jan 15;26(5):2171-6. doi: 10.1016/j.bios.2010.09.029. Epub 2010 Sep 21.

Abstract

Available techniques of X-ray detection have been under development due to specific shortcomings such as finite lifetime, low sensitivity, and post-processing requirements. Here we report on the fabrication of an X-ray sensor based on bacteriorhodopsin (BR) with a radius of r=3mm as the sensing area on a flexible substrate. The flexible X-ray detector can be placed on the targeted area for real-time monitoring of radiation dosage. We show that BR sensor is a potential candidate for such a powerful sensing device. For this purpose, we measure the electrical current generated by the BR sensor under different radiation dosages, energies and dose rates. This averaged current is in the range of nanoampere and is proportional to the dose rate of the received X-ray. The current also increases with the increase of radiation energy. BR radiation sensor can be readily miniaturized and is relatively easy to fabricate. The capability for real-time data collection and reusability are other advantages of this radiation sensor.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacteriorhodopsins / chemistry*
  • Bacteriorhodopsins / radiation effects*
  • Biosensing Techniques / instrumentation*
  • Conductometry / instrumentation*
  • Equipment Design
  • Equipment Failure Analysis
  • Radiometry / instrumentation*
  • X-Rays

Substances

  • Bacteriorhodopsins