Correlates and predictors of patient satisfaction with drug therapy and combined drug therapy and behavioral training for urgency urinary incontinence in women

Int Urogynecol J. 2011 Mar;22(3):327-34. doi: 10.1007/s00192-010-1287-x. Epub 2010 Oct 13.

Abstract

Introduction and hypothesis: The goal was to identify correlates of patient satisfaction with drug and behavioral treatments for urge-predominant incontinence, which may help tailor treatments to improve satisfaction.

Methods: Planned secondary analysis of a multi-center, clinical trial randomizing 307 women to 10 weeks of tolterodine alone or combined with behavioral training. Satisfaction was measured using the Patient Satisfaction Question (PSQ). Potential correlates included baseline demographics, incontinence characteristics and prior treatments, history and physical parameters, expectations of treatment success, and outcome variables including the Global Perception of Improvement (GPI) and Urogenital Distress Inventory (UDI).

Results: After multivariable analysis, every 10-point increase in UDI change score increased odds of satisfaction by 11% (OR 1.11; 1.04-1.19). Odds of satisfaction increased among women reporting "much better" on the GPI (OR 13.8; 4.94-38.60).

Conclusions: Treatment satisfaction for women with urge-predominant incontinence was associated with patient-related outcomes reflecting impression of improvement and bother from incontinence-related symptoms.

Trial registration: ClinicalTrials.gov NCT00090584.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Behavior Therapy / methods*
  • Benzhydryl Compounds / therapeutic use*
  • Combined Modality Therapy
  • Cresols / therapeutic use*
  • Female
  • Health Surveys
  • Humans
  • Middle Aged
  • Multivariate Analysis
  • Muscarinic Antagonists / therapeutic use*
  • Patient Satisfaction*
  • Phenylpropanolamine / therapeutic use*
  • Retrospective Studies
  • Tolterodine Tartrate
  • Treatment Outcome
  • Urinary Incontinence, Urge / therapy*

Substances

  • Benzhydryl Compounds
  • Cresols
  • Muscarinic Antagonists
  • Phenylpropanolamine
  • Tolterodine Tartrate

Associated data

  • ClinicalTrials.gov/NCT00090584