First report of Salmonella enterica serotype paratyphi A azithromycin resistance leading to treatment failure

J Clin Microbiol. 2010 Dec;48(12):4655-7. doi: 10.1128/JCM.00648-10. Epub 2010 Oct 13.

Abstract

The prevalence of Salmonella enterica serotype Paratyphi A infection is increasing, and multidrug resistance is a well-recognized problem. Resistance to fluoroquinolones is common and leads to more frequent use of newer agents like azithromycin. We report the first case of azithromycin resistance and treatment failure in a patient with S. Paratyphi A infection.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Azithromycin / pharmacology
  • Azithromycin / therapeutic use*
  • Drug Resistance, Bacterial*
  • Humans
  • Male
  • Middle Aged
  • Paratyphoid Fever / drug therapy*
  • Paratyphoid Fever / microbiology*
  • Salmonella paratyphi A / drug effects*
  • Salmonella paratyphi A / isolation & purification
  • Treatment Failure

Substances

  • Azithromycin