Abstract
In a background of high genomic HIV-1 variability with a predominance of CRF11_cpx and CRF22_01A1, we have studied the emergence of resistance mutations in isolates from Central African patients at failure of d4T-AZT/3TC/NVP-EFV plus two at failure of a PI-including regimen; the resistance mutations observed are those which are expected on HIV-1 subtype B.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Amino Acid Substitution / genetics
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Anti-Retroviral Agents / pharmacology*
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Anti-Retroviral Agents / therapeutic use
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Central African Republic
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Child
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Child, Preschool
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Drug Resistance, Viral*
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Genotype
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HIV Infections / drug therapy
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HIV Infections / virology*
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HIV-1 / drug effects*
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HIV-1 / genetics*
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HIV-1 / isolation & purification
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Humans
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Middle Aged
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Molecular Sequence Data
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Mutation, Missense*
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Sequence Analysis, DNA
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Treatment Failure
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Young Adult
Associated data
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GENBANK/HM117925
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GENBANK/HM117926
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GENBANK/HM117927
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GENBANK/HM117928
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