Relationship between bone metabolism and adipogenesis

V Carnevale; E Romagnoli; R Del Fiacco; J Pepe; C Cipriani; S Piemonte; L Carlucci; S Minisola

Relationship between bone metabolism and adipogenesis

J Endocrinol Invest. 2010;33(7 Suppl):4-8.

Authors

V Carnevale¹, E Romagnoli, R Del Fiacco, J Pepe, C Cipriani, S Piemonte, L Carlucci, S Minisola

Affiliation

¹ Unit of Internal Medicine, IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo (FG), Italy.

PMID: 20938218

Abstract

Several findings indicate that adipose tissue and bone have a complex reciprocal relationship. The two cells lineages share a common progenitor, and adipocyte endocrine activity may influence bone metabolism. Recent evidence from animal models suggests that bone cells may contribute regulating energy metabolism.

MeSH terms

Adipocytes / physiology
Adipogenesis / physiology
Adiponectin / physiology
Animals
Bone and Bones / drug effects
Bone and Bones / metabolism*
Cell Lineage
Energy Metabolism / physiology
Humans
Leptin / physiology
Osteoblasts / physiology
Osteocalcin / physiology

Substances

Adiponectin
Leptin
Osteocalcin