Long-term effects of cilostazol on the prevention of macrovascular disease in patients with type 2 diabetes mellitus

Diabetes Res Clin Pract. 2011 Jan;91(1):e11-4. doi: 10.1016/j.diabres.2010.09.009. Epub 2010 Oct 8.

Abstract

We analyzed the medical records of 884 type 2 DM patients who were taking different antiplatelet agents for more than 2 years. Based on the records, occurrences of cardiovascular events for 10 years were evaluated. The composite disease-free survival rate for cilostazol monotherapy group was similar to aspirin subgroup (p=0.133).

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aspirin / therapeutic use
  • Cardiovascular Diseases / epidemiology
  • Cardiovascular Diseases / prevention & control
  • Cerebrovascular Disorders / epidemiology
  • Cerebrovascular Disorders / prevention & control
  • Cilostazol
  • Diabetes Mellitus, Type 2 / complications*
  • Diabetes Mellitus, Type 2 / drug therapy*
  • Diabetic Angiopathies / epidemiology
  • Diabetic Angiopathies / prevention & control*
  • Disease-Free Survival
  • Drug Therapy, Combination
  • Female
  • Humans
  • Male
  • Medical Records
  • Middle Aged
  • Peripheral Arterial Disease / epidemiology
  • Peripheral Arterial Disease / prevention & control
  • Platelet Aggregation Inhibitors / therapeutic use*
  • Proportional Hazards Models
  • Republic of Korea / epidemiology
  • Retrospective Studies
  • Tetrazoles / therapeutic use*

Substances

  • Platelet Aggregation Inhibitors
  • Tetrazoles
  • Cilostazol
  • Aspirin