Sulfur-containing amides from Entada phaseoloides

Yao Xue Xue Bao. 2010 May;45(5):624-6.

Abstract

To study the chemical constituents of the Entada phaseoloides (L.) Merr., seeds of Entada phaseoloides were extracted with 70% ethanol at room temperature. Isolation and purification were performed by silica gel, reversed-phase silica gel column chromatography and semi-preparative HPLC. Structures of the pure compounds were established on the basis of spectral analysis. Four sulfur-containing amide compounds were isolated from the n-BuOH-soluble fraction and identified as entadamide A-beta-D-glucopyranosyl-(1-->3)-beta-D-glucopyranoside (1), entadamide A (2), entadamide A-beta-D-glucopyranoside (3) and clinacoside C (4). Compound 1 is a new compound. Compound 4 is isolated from the genus Entada for the first time.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acrylamides / chemistry
  • Acrylamides / isolation & purification*
  • Fabaceae / chemistry*
  • Molecular Structure
  • Plants, Medicinal / chemistry*
  • Seeds / chemistry
  • Thioglucosides / chemistry
  • Thioglucosides / isolation & purification*

Substances

  • Acrylamides
  • Thioglucosides
  • clinacoside C
  • entadamide A-beta-D-glucopyranosyl-(1-3)-beta-D-glucopyranoside
  • entadamide A