Abstract
Bacterial pneumonia can be a life-threatening disease that causes lung injury. A new study shows that accumulation of a phospholipid in the lung fluid in mice and humans worsens gas exchange during the microbial infection (pages 1120–1127). Clearance of this lipid may improve lung function during infection.
MeSH terms
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Adenosine Triphosphatases / physiology*
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Animals
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Cardiolipins / physiology*
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Humans
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Lung Injury / etiology*
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Mice
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Pneumonia, Bacterial / complications*
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Pulmonary Gas Exchange
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Pulmonary Surfactants / metabolism*
Substances
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Cardiolipins
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Pulmonary Surfactants
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Adenosine Triphosphatases
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ATP8B1 protein, human