Towards the discovery of new hypnotic agents: synthesis and preliminary pharmacological evaluation of a novel class of dibenzo[a,d]cycloheptene derivatives

ChemMedChem. 2010 Nov 8;5(11):1843-6. doi: 10.1002/cmdc.201000280.
No abstract available

MeSH terms

  • Cyclization
  • Dibenzocycloheptenes / chemical synthesis*
  • Dibenzocycloheptenes / chemistry
  • Dibenzocycloheptenes / pharmacology*
  • Humans
  • Hypnotics and Sedatives / chemical synthesis*
  • Hypnotics and Sedatives / chemistry
  • Hypnotics and Sedatives / pharmacology
  • Mianserin / analogs & derivatives
  • Mianserin / chemistry
  • Mianserin / pharmacology
  • Spiro Compounds / chemistry
  • Spiro Compounds / pharmacology
  • Structure-Activity Relationship

Substances

  • Dibenzocycloheptenes
  • Hypnotics and Sedatives
  • Spiro Compounds
  • Mianserin