New reactions of anticancer-platinum complexes and their intriguing behaviour under various experimental conditions

Dalton Trans. 2010 Nov 28;39(44):10601-7. doi: 10.1039/c0dt00506a. Epub 2010 Oct 5.

Abstract

The anticancer platinum complexes here described react with organic substrates (such as acids, alkenes, alkynes) and catalyze transformations that can occur in biomolecules which contain unsaturated functions. We have analyzed the role of the platinum complexes in the observed reactions and studied the progress of the detected transformations upon variation of the reaction conditions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acids / chemistry
  • Alkenes / chemistry
  • Alkynes / chemistry
  • Antineoplastic Agents / chemistry*
  • Catalysis
  • Models, Chemical
  • Organometallic Compounds / chemistry*
  • Platinum / chemistry*
  • Solvents / chemistry
  • Time Factors
  • Water / chemistry

Substances

  • Acids
  • Alkenes
  • Alkynes
  • Antineoplastic Agents
  • Organometallic Compounds
  • Solvents
  • Water
  • Platinum