Abstract
Budding yeast are not permeable to many drugs. This unit provides a protocol in which polygodial is used to permeabilize the cell membrane, thereby allowing budding yeast cells to be treated with drugs that otherwise would be ineffective.
© 2010 by John Wiley & Sons, Inc.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antifungal Agents / metabolism*
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Cell Membrane / drug effects*
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Cell Membrane / physiology*
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Cell Membrane Permeability / drug effects*
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Saccharomyces cerevisiae / drug effects*
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Saccharomyces cerevisiae / physiology*
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Sesquiterpenes / metabolism*
Substances
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Antifungal Agents
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Sesquiterpenes
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polygodial