Abstract
A new member of the phlebovirus genus, tentatively named Granada virus, was detected in sandflies collected in Spain. By showing the presence of specific neutralizing antibodies in human serum collected in Granada, we show that Granada virus infects humans. The analysis of the complete genome of Granada virus revealed that this agent is likely to be a natural reassortant of the recently described Massilia virus (donor of the long and short segments) with a yet unidentified phlebovirus (donor of the medium segment).
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Animals
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Antibodies, Viral / blood
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Base Sequence
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Chlorocebus aethiops
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Female
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Genome, Viral
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Humans
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Insect Vectors / virology
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Male
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Molecular Sequence Data
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Phlebotomus Fever / epidemiology
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Phlebotomus Fever / virology*
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Phylogeny
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Psychodidae / virology*
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Reassortant Viruses
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Sandfly fever Naples virus / classification*
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Sandfly fever Naples virus / genetics*
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Sandfly fever Naples virus / immunology
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Seroepidemiologic Studies
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Vero Cells
Associated data
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GENBANK/GU135606
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GENBANK/GU135607
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GENBANK/GU135608