Implementing a rational and consistent nomenclature for serine/arginine-rich protein splicing factors (SR proteins) in plants

Plant Cell. 2010 Sep;22(9):2926-9. doi: 10.1105/tpc.110.078352. Epub 2010 Sep 30.

Abstract

Growing interest in alternative splicing in plants and the extensive sequencing of new plant genomes necessitate more precise definition and classification of genes coding for splicing factors. SR proteins are a family of RNA binding proteins, which function as essential factors for constitutive and alternative splicing. We propose a unified nomenclature for plant SR proteins, taking into account the newly revised nomenclature of the mammalian SR proteins and a number of plant-specific properties of the plant proteins. We identify six subfamilies of SR proteins in Arabidopsis thaliana and rice (Oryza sativa), three of which are plant specific. The proposed subdivision of plant SR proteins into different subfamilies will allow grouping of paralogous proteins and simple assignment of newly discovered SR orthologs from other plant species and will promote functional comparisons in diverse plant species.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Arabidopsis / chemistry*
  • Arabidopsis / genetics
  • Nuclear Proteins / classification*
  • Oryza / chemistry*
  • Oryza / genetics
  • Plant Proteins / classification*
  • RNA-Binding Proteins / classification*
  • Serine-Arginine Splicing Factors
  • Terminology as Topic

Substances

  • Nuclear Proteins
  • Plant Proteins
  • RNA-Binding Proteins
  • Serine-Arginine Splicing Factors