Precise control of protein concentration in living cells

Angew Chem Int Ed Engl. 2010 Nov 2;49(45):8458-61. doi: 10.1002/anie.201003073.

Authors

Hubert D Lau¹, Junko Yaegashi, Balyn W Zaro, Matthew R Pratt

Affiliation

¹ Department of Chemistry, University of Southern California, 840 Downey Way, LJS 250, Los Angeles, CA 90089-0744, USA.

PMID: 20878685
DOI: 10.1002/anie.201003073

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Substitution
Animals
Anti-Bacterial Agents / pharmacology
Flow Cytometry
Green Fluorescent Proteins / chemistry
Green Fluorescent Proteins / metabolism
Mice
Mutagenesis, Site-Directed
NIH 3T3 Cells
Protein Structure, Tertiary
Recombinant Fusion Proteins / chemistry
Recombinant Fusion Proteins / genetics
Recombinant Fusion Proteins / metabolism
Sirolimus / pharmacology
Tacrolimus Binding Proteins / chemistry*
Tacrolimus Binding Proteins / genetics
Tacrolimus Binding Proteins / metabolism
Ubiquitin / chemistry
Ubiquitin / genetics
Ubiquitin / metabolism

Substances

Anti-Bacterial Agents
Recombinant Fusion Proteins
Ubiquitin
Green Fluorescent Proteins
Tacrolimus Binding Proteins
Sirolimus