In this chapter, we discuss some of the situations in which an asthmatic patient may require different management to usual treatment has been discussed in previous chapters. It is important to recognize these special situations in the asthmatic patient, because if we do so may be serious complications and unnecessary in its evolution. Although the list can be quite extensive, this section will refer to asthma during natural hormonal changes like pregnancy or the menstrual cycle, the relationship with intolerance to NSAIDs, care needs asthmatic patients before and after surgery, and ultimately the patient who is facing an event of anaphylaxis.