Subacute osteomyelitis masquerading as primary bone sarcoma: report of six cases

Surg Infect (Larchmt). 2010 Oct;11(5):475-8. doi: 10.1089/sur.2009.011.

Abstract

Background: We report a series of six immunocompetent patients who were believed initially to have primary bone sarcomas, but turned out to have subacute osteomyelitis.

Methods: Case report and review of relevant literature.

Results: All our patients were treated with antibiotics and recovered fully from the infection. Only one patient had a recurrence with the same offending microorganism, which resolved after a longer period of intravenous antibiotic.

Conclusions: Subacute osteomyelitis and bone tumors can be similar in presentation, and the key to proper diagnosis is histopathological and microbiological confirmation in biopsy specimens.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Bone and Bones / diagnostic imaging
  • Bone and Bones / pathology
  • Child
  • Diagnosis, Differential
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Osteomyelitis / diagnosis*
  • Osteomyelitis / drug therapy
  • Osteomyelitis / pathology*
  • Osteosarcoma / diagnosis*
  • Osteosarcoma / pathology*
  • Radiography
  • Treatment Outcome
  • Young Adult

Substances

  • Anti-Bacterial Agents