A liposome-based energy conversion system for accelerating the multi-enzyme reactions

Phys Chem Chem Phys. 2010 Nov 14;12(42):13904-6. doi: 10.1039/c0cp00556h. Epub 2010 Sep 17.

Abstract

We report the first example of a liposome-based energy conversion system that is useful for entrapping enzymes and NAD coenzyme to accelerate multi-step enzymatic reactions. The liposome generates a much higher catalytic current compared with the non-liposome system, which is in good consistency with numerical simulations.

MeSH terms

  • Alcohol Dehydrogenase / chemistry
  • Alcohol Dehydrogenase / metabolism
  • Biocatalysis
  • Dihydrolipoamide Dehydrogenase / chemistry
  • Dihydrolipoamide Dehydrogenase / metabolism
  • Electrochemistry / methods*
  • Enzymes, Immobilized / chemistry*
  • Enzymes, Immobilized / metabolism*
  • Ethanol / metabolism
  • Kinetics
  • Liposomes / chemistry*
  • NAD / metabolism
  • Oxidation-Reduction

Substances

  • Enzymes, Immobilized
  • Liposomes
  • NAD
  • Ethanol
  • Alcohol Dehydrogenase
  • Dihydrolipoamide Dehydrogenase