Anti-herpetic activities of chemical components from the Brazilian red alga Plocamium brasiliense

Wilton José Ferreira; Rodrigo Amaro; Diana Negrão Cavalcanti; Claudia Moraes de Rezende; Viveca Antonia Giongo Galvão da Silva; Juliana Eymara Barbosa; Izabel Christina Nunes de Palmer Paixão; Valéria Laneuville Teixeira

Anti-herpetic activities of chemical components from the Brazilian red alga Plocamium brasiliense

Nat Prod Commun. 2010 Aug;5(8):1167-70.

Authors

Wilton José Ferreira¹, Rodrigo Amaro, Diana Negrão Cavalcanti, Claudia Moraes de Rezende, Viveca Antonia Giongo Galvão da Silva, Juliana Eymara Barbosa, Izabel Christina Nunes de Palmer Paixão, Valéria Laneuville Teixeira

Affiliation

¹ Programa de Pós-Graduação em Química, Instituto de Química, Universidade Federal Fluminense, Niterói, RJ, Brazil.

PMID: 20839610

Abstract

The CH2Cl2 crude extract and a fraction enriched with halogenated monoterpenes of the Brazilian red alga Plocamium brasiliense were evaluated for cytotoxicity and against the virus HSV-1. The extract showed low cytotoxicity compared with the fraction containing monoterpenes. The crude extract showed, in vitro, a high reduction of infectivity of the virus HSV-1.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antiviral Agents / pharmacology*
Brazil
Herpesvirus 1, Human / drug effects*
Monoterpenes / pharmacology*
Plocamium / chemistry*

Substances

Antiviral Agents
Monoterpenes