Preeclampsia as a female-specific risk factor for chronic hypertension

Maturitas. 2010 Dec;67(4):321-6. doi: 10.1016/j.maturitas.2010.08.002. Epub 2010 Sep 15.

Abstract

Preeclampsia is a complication of pregnancy that has also long term effects on maternal health. Several epidemiologic studies have shown an increased risk for cardiovascular morbidity (relative risk [RR] 2.3) and mortality (RR 2.3) in women after a history of preeclampsia. The chance to develop chronic hypertension afterwards is twofold to 10 times higher in affected women, compared with women after normotensive pregnancies. As hypertension is a major cardiovascular risk factor, early detection and treatment is mandatory to reduce the risk of future cardiovascular disease. Data on (cost)-effectiveness of cardiovascular screening programs in women after preeclampsia are currently lacking and there are no recommendations yet for prevention in the guidelines. We recommend regularly preventive blood pressure measurements after high risk pregnancies. More research is needed to identify women who will profit most of early intervention.

Publication types

  • Review

MeSH terms

  • Blood Pressure
  • Chronic Disease
  • Female
  • Humans
  • Hypertension / diagnosis
  • Hypertension / etiology*
  • Hypertension / prevention & control
  • Pre-Eclampsia*
  • Pregnancy
  • Risk Factors