[The mechanisms of the antioxidant action of shielded phenols in biological membranes. The effects of 4-methyl-2,6-di-tert-butylphenol (ionol) and its derivatives]

E Serbinova; M Kharfuf; L Iu Ukhin; V P Komissarov; A N Erin; S Rakovski; V Savov; V E Kagan

[The mechanisms of the antioxidant action of shielded phenols in biological membranes. The effects of 4-methyl-2,6-di-tert-butylphenol (ionol) and its derivatives]

Biull Eksp Biol Med. 1990 Nov;110(11):486-9.

[Article in Russian]

Authors

E Serbinova, M Kharfuf, L Iu Ukhin, V P Komissarov, A N Erin, S Rakovski, V Savov, V E Kagan

PMID: 2083329

Abstract

According to Bulgarian-Soviet program "Biostab" we studied characteristics of different phenol compounds (ionol derivatives). The aim of the present study is to determine antiradical and antioxidant activity of a number of ionol derivatives in pure chemical systems and in different membrane fractions of a natural origin.

Publication types

English Abstract

MeSH terms

Animals
Antioxidants*
Butylated Hydroxytoluene / pharmacology*
Free Radicals
Intracellular Membranes / drug effects*
Intracellular Membranes / metabolism
Lipid Peroxidation / drug effects
Luminescent Measurements
Membrane Lipids / metabolism
Microsomes, Liver / drug effects*
Microsomes, Liver / metabolism
Phenols / pharmacology*
Rats

Substances

Antioxidants
Free Radicals
Membrane Lipids
Phenols
Butylated Hydroxytoluene