Abstract
The Staudinger reaction of unprotected azido-peptides with silylated phosphinic acids and esters on the solid support offers a straightforward acid-free entry to different phosphonamidate peptide esters or acids under mild conditions in high purity and yield.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amides / chemistry*
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Esters / chemistry*
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Molecular Structure
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Organosilicon Compounds / chemistry*
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Phosphinic Acids / chemistry*
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Phosphopeptides / chemical synthesis*
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Phosphopeptides / chemistry
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Stereoisomerism
Substances
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Amides
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Esters
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Organosilicon Compounds
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Phosphinic Acids
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Phosphopeptides