Linear childhood discoid lupus erythematosus following the lines of Blaschko: successfully treated with topical tacrolimus

Pediatr Dermatol. 2011 Mar-Apr;28(2):205-7. doi: 10.1111/j.1525-1470.2010.01249.x. Epub 2010 Sep 1.

Abstract

The linear arrangement of discoid lupus erythematosus is uncommon. Here, we report a 6-year-old Japanese girl with linear discoid lupus erythematosus following the lines of Blaschko on her face and neck. Topical tacrolimus treatment improved the eruptions. The present case also indicated the important role of epidermal and dermal cells as well as immune cells in the pathogenesis of cutaneous lupus erythematodes.

Publication types

  • Case Reports

MeSH terms

  • Administration, Topical
  • Biopsy
  • Child
  • Face / pathology*
  • Female
  • Humans
  • Immunosuppressive Agents / administration & dosage*
  • Lupus Erythematosus, Discoid / drug therapy*
  • Lupus Erythematosus, Discoid / pathology*
  • Tacrolimus / administration & dosage*

Substances

  • Immunosuppressive Agents
  • Tacrolimus