Utility of CT Scan in detection of melamine--associated urinary stones

Indian J Pediatr. 2010 Dec;77(12):1405-8. doi: 10.1007/s12098-010-0183-1. Epub 2010 Sep 7.

Abstract

Objective: To detail the utility of CT scan in detection of urinary stones induced by melamine tainted formula.

Material and methods: A total of 1062 children fed with melamine-contaminated infant formula were screened for urinary stones in our institute from September through December 2008. Ultrasonography of the urinary tract system was performed in all these children. If the children with suspected stones or severe obstruction were presented after ultrasound examination, the multi-detector row CT urographic examination was advocated subsequently.

Results: Ultrasound examination in combination with multi-detector row CT urography could increase the diagnostic rate from 3.4% (36/1062) by ultrasound examination alone to 4.6% (49/1062).

Conclusions: The specificity and sensitivity of the multi-detector row CT urographic examination is higher than ultrasonography.

MeSH terms

  • Child
  • Child, Preschool
  • Cohort Studies
  • Female
  • Food Contamination
  • Humans
  • Infant
  • Infant Formula / chemistry*
  • Male
  • Retrospective Studies
  • Tomography, X-Ray Computed*
  • Triazines / adverse effects*
  • Urinary Calculi / chemically induced*
  • Urinary Calculi / diagnosis*
  • Urinary Calculi / therapy

Substances

  • Triazines
  • melamine