Abstract
We investigated the hemorheologic profile in 110 women undergoing controlled ovarian stimulation and provide evidence that smokers and women with body mass index>25 kg/m2 exhibit alterations of rheologic profile. A progressive increase of whole-blood viscosity throughout the ovarian stimulation cycle was observed; deformability and aggregation of erythrocytes decreased from baseline to the beginning of recombinant FSH administration, then remained unchanged throughout the next days; hematocrit mildly decreased during the last days of recombinant FSH administration; and fibrinogen and cholesterol levels decreased and increased, respectively, throughout the stimulation cycle.
Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
MeSH terms
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Adult
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Blood Flow Velocity / drug effects
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Chorionic Gonadotropin / administration & dosage
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Chorionic Gonadotropin / adverse effects
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Erythrocyte Aggregation / drug effects
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Erythrocyte Deformability / drug effects
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Female
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Fertility Agents, Female / administration & dosage
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Fertility Agents, Female / adverse effects
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Follicle Stimulating Hormone / administration & dosage
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Follicle Stimulating Hormone / adverse effects
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Hemorheology / drug effects*
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Hormones / administration & dosage*
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Hormones / adverse effects
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Humans
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Infertility, Female / epidemiology
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Infertility, Female / therapy*
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Leuprolide / administration & dosage
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Leuprolide / adverse effects
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Ovulation Induction*
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Risk Factors
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Sperm Injections, Intracytoplasmic*
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Vascular Diseases / chemically induced
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Vascular Diseases / epidemiology
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Young Adult
Substances
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Chorionic Gonadotropin
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Fertility Agents, Female
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Hormones
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Follicle Stimulating Hormone
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Leuprolide