Coupling among electroencephalogram gamma signals on a short time scale

Comput Intell Neurosci. 2010:2010:946089. doi: 10.1155/2010/946089. Epub 2010 Jul 29.

Abstract

An important goal in neuroscience is to identify instances when EEG signals are coupled. We employ a method to measure the coupling strength between gamma signals (40-100 Hz) on a short time scale as the maximum cross-correlation over a range of time lags within a sliding variable-width window. Instances of coupling states among several signals are also identified, using a mixed multivariate beta distribution to model coupling strength across multiple gamma signals with reference to a common base signal. We first apply our variable-window method to simulated signals and compare its performance to a fixed-window approach. We then focus on gamma signals recorded in two regions of the rat hippocampus. Our results indicate that this may be a useful method for mapping coupling patterns among signals in EEG datasets.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Action Potentials / physiology
  • Algorithms*
  • Animals
  • Brain / physiology*
  • Brain Waves / physiology*
  • Computer Simulation*
  • Cortical Synchronization / physiology
  • Electrodes / standards
  • Electroencephalography / methods*
  • Hippocampus / physiology
  • Humans
  • Neurons / physiology
  • Rats
  • Signal Processing, Computer-Assisted*
  • Time Factors