Addressing protein-protein interactions with small molecules: a Pro-Pro dipeptide mimic with a PPII helix conformation as a module for the synthesis of PRD-binding ligands

Angew Chem Int Ed Engl. 2010 Sep 17;49(39):7111-5. doi: 10.1002/anie.201001739.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Dipeptides / chemistry*
  • Ligands
  • Magnetic Resonance Spectroscopy
  • Peptides / chemical synthesis
  • Peptides / chemistry*
  • Proline-Rich Protein Domains*
  • Protein Binding
  • Protein Interaction Domains and Motifs
  • Protein Structure, Secondary
  • Protein Structure, Tertiary
  • Stereoisomerism

Substances

  • Dipeptides
  • Ligands
  • Peptides
  • prolyl-proline