Abstract
Silver nanoparticles made easy: A simple, effective, and one-pot method toward the synthesis of a defined macrocycle-silver nanoparticle system in water has been described (see figure). Interestingly, cucurbituril (CB)[7]-protected AgNPs showed significantly increased cytotoxicity against MCF-7 and NCI-H358 cancer cells, as demonstrated by models in vitro.
Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Bridged-Ring Compounds / chemistry*
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Bridged-Ring Compounds / therapeutic use
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Cell Line, Tumor
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Cell Survival / drug effects
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Humans
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Imidazoles / chemistry*
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Imidazoles / therapeutic use
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MCF-7 Cells
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Metal Nanoparticles / chemistry*
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Metal Nanoparticles / toxicity
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Neoplasms / drug therapy
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Particle Size
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Silver / chemistry*
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Sodium Hydroxide / chemistry
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Water / chemistry
Substances
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Bridged-Ring Compounds
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Imidazoles
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cucurbit(7)uril
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Water
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Silver
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Sodium Hydroxide